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Introducing GeneMarker for MS-MLPA.

DNA methylation is the addition of a methyl group to a piece of DNA, specifically to cytosines located in CG dinucleotide repeat regions. Regions of the genome containing a high frequency of these dinucleotides are referred to as CpG islands (1) and are often located in the promoter region of genes. Virtually all vertebrate animals have methylation sites in their genome. In humans, approximately 1% of DNA bases undergo DNA methylation

GeneMarker DNA analysis software has been successfully paired with the Multiplex Ligation-dependent Probe Amplification (MLPA®) technique for detecting genetic deletions and duplications in various diseases including cancer. For more details, download the PDF by clicking on the link below.

 

 

 

 

 For more details, download the MS-MLPA Application Note PDF PDF icon (139 Kb)

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